The Zanzibar II-class cruisers were an upgrade from the Zanzibar-class, gaining an additional four two-barrel beam turrets, which made the ship as powerful as a Federation's Magellan-class battleship. It was capable of carrying eight mobile suits, and same as the original, it could replace four mobile suits with a mobile armor on its hangar.
The ship also featured a mobile suit launch catapult on the side of its hull, as well as a rear launch or recovery deck located between the engines. It was also capable of better atmospheric flight due to a more aerodynamic design and the increase of thrusters, mounting six primary thrusters instead of four.
At least one Zanzibar II-class ship, the Lili Marleen, was used as a flagship for the Cima Fleet during Aiguille Delaz's Operation Stardust. It was destroyed during the final phase of Operation Stardust by the EFF's prototype mobile weapon, the RX-78GP03 Gundam "Dendrobium".