Yusuke Amamiya, Jou Ohara, Megumi Misaki, Takuji Yano, and Mari Aikawa sought to create a suit strong enough for space exploration. However, three of their fellow classmates and dear friends, Kenji Tsukigata, Rui Senda, and Gou Omura, felt their talents are being wasted and leave to join an evil organization called Volt who offers them to raise their full scientific potential. When they refuse, Kenji kills Takuji and Mari and the three students leave with Volt. Soon after, one of the professors at the school, Doctor Hoshi, pitches in to help Yusuke and his friends complete the suits so they can serve to prepare against Volt.

Two years later, with that Kenji, Rui, and Gou now known as Doctors Kemp, Mazenda, and Obular, Volt begins its attack by devastating Academia Island. As a result, Yusuke, Jou, and Megumi take up the suits they created and become the Liveman to battle against their former classmates and Volt. Though they managed to get Gou to leave Volt, the organization recruits new members in Doctor Ashura and the aliens Guildos and Butchy.